"Claire Redfield is a main character and one of the major protagonists in the Resident Evil series of survival horror games. A 19 year old college student and motorcyclist, she is the younger sister of S.T.A.R.S. member Chris Redfield, another major character in the series. She is one of the main protagonists in Resident Evil 2, Resident Evil Code Veronica X and Resident Evil: Revelations 2. She was voiced by the Canadian-American actress Alyson Court until Resident Evil Operation Raccoon City. In Resident Evil Revelations 2, she is voiced by an unknown actress (credited as Jamie Baker) while in the 2019 remake version of Resident Evil 2 until the upcoming movie Resident Evil: Death Island, she is voiced by Stephanie Panisello.

Claire has long auburn hair tied to a ponytail and blue eyes. Claire's original outfit in Resident Evil 2 consisted of a black short-sleeved, short-legged cycling skinsuit worn under a pink vest with a "Made in Heaven" design on the back (which she gave it to Sherry at the end of the game), pink-colored jean shorts, brown boots, and black riding gloves. Her special outfit in the game consists of a leather jacket and pants with a "Let Me Live" design on the back and a red bandanna. The "Let Me Live" design is also featured on a different outfit in Resident Evil Code Veronica. The "Made in Heaven" design seems to show her connection to Chris who sported this on the back of his special outfit in the first game.

In Darkside Chronicles and Operation Racoon City, Claire has a two-piece suit, her pink vest has an extended collar. She wears blue denim short shorts with a brown side pouch and western style cowboy boots. She also has rider goggles on her neck. In the former game and Mercenaries 3D, Claire has fingerless gloves, and her jeans have holes in each side.

In Resident Evil Code Veronica, Claire's hair was still tied in a ponytail and her eyes were blue. She wore a red denim vest with three flame designs at the left side, and at the back it had a "Let me Live" design on her vest, underneath a black short sleeve low cut shirt that bared her midriff, blue jeans with a red belt and brown shoes. She also wore brown fingerless gloves and a pink choker on her neck. Since Code Veronica, Claire has been depicted to have long auburn hair and blue eyes during cutscenes and her outfits were either pink or red.

In the animated film Resident Evil Degeneration, Claire's hair was red instead of auburn. She was dressed casually in an off white short sleeve button shirt with a dark pink turtleneck shirt, dark khaki pants with a brown belt to her waist and brown shoes.

Claire later regains her Island default outfit in Resident Evil Revelations 2 from the animated CGI series, Resident Evil: Infinite Darkness. her red leather jacket is now the same color as her leather jacket in Resident Evil 2 Remake and has black designs at the edge of the collar of her leather jacket, her belt is now black to match up her biker boots and her jeans are now medium blue. She also wears a brown watch on her left wrist. When meeting with Leon, she appears to wear her red eyeglasses before she removes it.

When she finds the evidence regarding the Penamstan Incident while staying at the motel, Claire wears a red tank top, black trousers, and black shoes. She sometimes wears her red eyeglasses and her brown watch.

In Resident Evil Revelations 2, Claire wears a white long sleeve button-up shirt along with her signature red leather sports jacket, blue jeans with a matching belt and black biker boots. She later receives a monitoring bracelet on her left wrist following her co-workers including Moira being captured by the militia led by Alex. She also gains a black nylon utility belt on her waist and a gun holster on her right where she keeps her handgun and knife. Her Island default outfit is later worn by Ali Larter in Resident Evil: The Final Chapter only her jeans appear black instead of blue.

At 1 point during Barry's story which takes place 6 months later, Claire's hair was cutten short. She wears a red long sleeve v-neck shirt with black pocket on the left side and a black shoulder holster. However she maintains her jeans with a matching blue belt and boots as well. She also wears black fingerless gloves, a matching utility belt and black and orange rider goggles on her neck. She is no longer wearing the monitoring bracelet on her left wrist due to its removal after being treated in the hospital. The outfit that she wears was her Sniper outfit which later becomes playable in Raid mode.

In the epilogue, Claire wears her island default outfit from the beginning of the game, but her hair remains short.

She also wears four DLC costumes in the game, which is her Sniper outfit, her classic attire in Resident Evil 2, a cowboy outfit and her TerraSave outfit. Her cowboy outfit has her wearing a red and black short sleeved mini collared button plaid top with a ribbon tied at the center that exposes more of her midriff, pale blue denim short shorts with a large white side belt around her waist and white cowboy boots. She also let her long auburn hair loose while wearing a white cowboy hat. She is accessorized with a large dark blue bracelet on her right that resembles a gauntlet and retains the monitoring bracelet on her left.

In the manga series BIOHAZARD Heavenly Island which takes place after Resident Evil 6, Claire's short hair has grown into a medium length and it was loose. Her outfit is a combination between her film version in Resident Evil: Afterlife and her Sniper outfit in Resident Evil: Revelations 2.

She wears a red leather vest with a white sleeveless loose shirt with a knot tied at the left side on her waist, she maintains her pants, black biker boots and her nylon utility belt from her Sniper outfit in Revelations 2 and her belt is now brown and she no longer wears gloves but only wears a black watch on her left wrist.

Later she wears a similar outfit as the first outfit only her top is replaced with a dark blue tank top, her pants became pale blue and her medium auburn hair is now tied in a ponytail. She later let her hair loose at the end of the manga while wearing a short sleeved button-up flannel shirt, jeans and black rider boots when she reported to her brother Chris about the Sonido de Tortuga incident by typing from her laptop.

In Resident Evil 2 Remake, Claire now has smaller and younger features, as well as light brown hair instead of auburn seen in Revelations 2. Instead of wearing her cycling skinsuit in the original Resident Evil 2, she wears a combination between her red vest in CODE: Veronica and her jeans with holsters in Revelations 2. She now wears a red leather jacket with an extended collar, a black tank top with a white undershirt beneath it, indigo jeans with a black belt along with a gun holster on her right leg, and brown biker boots. The "Made in Heaven" logo is now the same color as her jacket and wears a necklace with a sharp knife design. She later gives her jacket to Sherry, and from that part on, wears her tank top and her undershirt beneath it.

In the movie, Resident Evil: Death Island, Claire's hair is dark auburn and retains her main look in Resident Evil: Infinite Darkness. Her main outfit is similar to her appearance in the remake version of Resident Evil 2; she maintains her red leather jacket with extended collar and several pockets, her black tank top and white undershirt are replaced with a black short sleeve undershirt, her jeans are dark blue and her biker boots are black.

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