"Take care, it's a big Wasteland. But you'd know that better than me, right?
Moira Brown, Fallout 3.

"Never fear, Gordon, she's de-beaked and completely harmless. The worst she might do is attempt to couple with your head. Fruitlessly!"
Dr. Isaac Kleiner, Half-life 2.

"That's Mushy Snugglebites' badonkadonk. She's my main squeeze. Lady's got a gut fulla' dynamite and a booty like POOOW!"
Tiny Tina, Borderlands 2.

"Ben is young and stupid, and I think, harmless."
Lee Everett, The Walking Dead.

"It's a mathematical certainty that 80% of you are going to lose tonight. And 100% of you will eventually die. Math is fun, don't you think?"
GLaDOS, Poker Night 2.

"Let's see: I'm Francis, and that's Grandpa Bill, and - there's *zombies* out here! *Open the ♥♥♥♥♥♥♥ DOOR!"
Francis, Left 4 Dead.